Density Gradient Equilibrium (DGE) AUC Resources Center
Based on the gold-standard preparative density gradient ultracentrifugation (DGUC), density gradient equilibrium analytical ultracentrifugation (DGE-AUC) makes method optimization and analysis easy and relatable. DGE-AUC is a direct measurement method, not relying on complex computations – if you see a peak, it’s real and you can quantify it.
DGE experiments utilize an easy-to-analyze method that characterizes empty/full viral capsids with significantly less sample requirements than other methods.
To learn more about DGE-AUC, explore these documents:
Getting Started with DGE-AUC Analysis
This reference guide describes how to import, plot, and analyze DGE-AUC data in Origin in only a few minutes.
Choosing DGE-AUC
Summary of when DGE-AUC is a good characterization option and its benefits.
Adapting the Power of Density Gradient Separations for Gene Therapy Analytics
A poster introducing the technique of using cesium chloride density gradients in the AUC and an articulation of those benefits.
Characterizing Viral Vector Fullness in Density Gradient Separations
Known as density gradient equilibrium analytical ultracentrifugation (DGE-AUC), it’s a simplified method that provides high-resolution benefits along with numerous advantages over the current gold standard sedimentation velocity AUC.
