CD208 (DC-LAMP) Antibodies

The DC-LAMP antigen (70-90 kDa) is a new member of the LAMP (lysosome-associated membrane protein) family. As other LAMP members such as CD68, DC-LAMP is a type I integral membrane protein of 416 amino acid residues, highly glycosylated (7 N- and some O‑glycosylation sites), with 90% of the molecule located in the lumen of lysosomes. DC-LAMP is specifically expressed by those mature dendritic cells (DC) located in T cell areas of lymphoid tissues, which are known as interdigitating dendritic cells (IDC). A direct correlation between the expression of DC-LAMP and that of other maturation markers such as CD86 has been established. DC-LAMP first appears in the MHC Class II compartment, suggesting an important contribution of DC-LAMP to the processing of exogenous antigens.
Clone: 104.G4 Isotype: IgG1 Mouse
In flow cytometry, the 104.G4 antibody shows intracytoplasmic staining of DCs derived either from CD34+ cell cultures activated with TNFα and CD40L, or from monocyte cultures activated with TNFα, LPS and CD40L.
Resources + Tools
FAQs Panel Design Product Listing Quality Standards Request a Quote Software

Explore CD208 Antibodies

Content and Resources

Flow Cytometry 2022 Catalog Outside US
Clinical Single Color Antibodies Outside US version
CD chart For identification of cell surface molecules
Immunophenotyping reference table - For haematopoietic malignancies Poster - Immunophenotyping reference table - For haematopoietic malignancies
How do I preserve sensitivity? Poster - How to preserve sensitivity