CD103-SNv786, 2G5, 0.5 mL, ASR

Product No:C78085

The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin αE subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β7 chain. CD103 is expressed on mucosa-associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. αEβ7 binds to E-cadherin on epithelial cells. Activation and TGFβ-1 induce CD103 expression.

Product Specifications

Format Liquid
Specificity CD103
Form SNv786
Clone 2G5
Isotype IgG2a Mouse
Cross Reactivity Indian Rhesus, Sooty Mangabey
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced C78085

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