
Cell-Free Technology and Acoustic Liquid Handling Are Helping Tierra Disrupt Natural Product Discovery Duration: 1 hour 28 seconds If you want to disrupt the natural products market, try combining acoustic liquid handling technology with advances in cell-free approaches. In this webinar, Zachary Sun, CEO of Tierra Biosciences (formerly Synvitrobio), shares how his company is doing just that using the Echo Liquid Handler. March English
An End-to-End Automated Workflow for High-Throughput SARS-Cov-2 Sequencing and Surveillance Duration: 59 minutes 56 seconds In this webinar, we highlight the collaboration between the European Molecular Biology Laboratory (EMBL), New England Biolabs (NEB), and Beckman Coulter Life Sciences to develop an automated high-throughput NGS library prep workflow for SARS-CoV-2 surveillance using the NEBNext ARTIC SARS-CoV-2 Library Prep Kit (Illumina) and the Biomek i7 Hybrid NGS Workstation. March
Cell Counting & Viability: Faster Results Through Automation Duration: xx minutes (x Videos at x minutes each) You will learn how the Vi-CELL BLU automates the entire analysis process – sample aspiration, trypan blue mixing, image analysis and instrument cleaning – to revolutionize the speed, reliability and reproducibility of results, and provides critical information manual cell counting methods simply cannot offer. Speaker: Uwe Killemann Field Marketing Manager Europe Beckman Coulter Life Sciences November
Avoid Pitfalls When Automating Cell Viability Counting for Biopharmaceutical Quality Control Duration: 48 minutes 17 seconds This educational webinar covers various modern automated cell counter technology, common pitfalls and how to avoid them. Includes discussion of the atuomated Trypan Blue cell counting method on the Vi-CELL XR. May English
Changes to USP <1788>: Determination of Subvisible Particle Matter from the HIAC and Coulter Counters Duration: xx minutes (x Videos at x minutes each) A revised version of the USP chapter on Subvisible Particulate Matter USP<1788> became official on 1st May 2021. USP<1788> is meant to expand on the information given in the chapters <787>, <788> and <789> to include for the first time the use of Flow Imaging techniques to provide orthogonal complimentary information to the HIAC high accuracy particle counter used in the compendial Light Obscuration Limit Test. June
Taking the Tricky Out of Automating NGS Sample Prep Duration: 14 minutes 30 seconds Presentation addresses challenging tasks in NGS (and other) workflows. Resources, demonstrated methods, instruments and techniques from Beckman Coulter also covered. May
Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler Duration: 52 minutes 41 seconds In this webinar, we show how prototyping CRISPR components can be accelerated by combining a cell-free transcription and translation (TXTL) system with an Echo Acoustic Liquid Handler (LH) from Beckman Coulter Life Sciences. March
Automation-Enabled LC-MS Analysis of Biologics Duration: 14 minutes 50 seconds This is a webinar discussing the Analysis of Biologics June
Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler Duration: 44 minutes and 30 seconds This webinar is part two of a two-part series on abstract cell-free expression. March
Characterization of Extracellular Vesicles with Nanoscale Flow Cytometry Duration: 49 minutes 14 seconds How to set up a flow cytometer for nanoparticle analyses February
Automation of PCR Setup and AMPure XP Purification using the Biomek 4000 Workstation Duration: 33 minutes 55 seconds This webinar covers PCR Setup and AMPure XP cleanup applications using the Biomek 4000. May
Characterizing Viruses: From Deadly Pathogens to the Workhorses of Gene Therapy Duration: 1 hour 3 minutes 6 seconds In this webinar, Dr. Bhattacharya will discuss the role of analytical ultracentrifugation (AUC) in uncovering the biophysics of these therapeutic targets. We will discuss typical case examples, including one where AUC is used to determine the dimerization affinity of SARS-CoV-2 protease. July
Avoiding the Perils of Hidden Requirements Duration: 14 minutes 7 seconds This video presentation covers important considerations and sometimes overlooked requirements when selecting an integration partner. May
Choosing the Right TOC Analyzer for a Pharmaceutical QC Laboratory Duration: 58 minutes, 9 seconds Hear Tony Harrison discuss the regulations for total organic carbon in pharmaceutical water, the typical measurement technologies that are used by TOC analyzers in pharmaceutical water analysis quality control, and lastly hear the introduction of a lab quality control analyzer that has been optimized for laboratory QC applications. April English
Basic Research Signaling Applications Duration: 55 minutes 39 seconds Basic signaling applications in life sciences research. May
The Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals Duration: 1 hour 2 minutes 20 seconds This webinar covers the key attributes of AUC as a highly effective technique for characterizing viral vectors for viral gene therapy delivery systems May English
Analytical Ultracentrifugation in the Biopharmaceutical Industry Duration: 1 hour 4 minutes 34 seconds Dr. Alexander Bepperling focuses on the data analysis tools to achieve high precision when analyzing biopharmaceutical products due to an interest in minor species of about 1-2% usually comprising of the total protein content. He focuses on the data analysis done in SEDFIT. Learn how to set up continuous c(S) distribution analysis as implemented with SEDFIT software for enhanced reproducibility during a study of many batches of one protein. Also covers applications of sedimentation equilibrium (SE) for screening weak interactions and determining detergent binding to proteins. May English
Analytical Ultracentrifugation in Nanoparticle Analysis Duration: 1 hour 1 minutes 43 seconds Joshua Robinson covers the utility of fractionation in the investigation of complex mixtures and polydisperse samples as well as versatility of analytical ultracentrifugation (AUC) for colloid chemistry. He quickly reviews analytical ultracentrifugation (AUC) theory, then discusses deconstructing nano-constructs and how AUC has been used in recent literature to really probe the underlying structure of nano-constructs, nanomaterials. Other topics covered include nanoparticle sample preparation, as well as Beckman Coulter's research and future perspectives. May English
Addressing the Challenges of Purification & Quality Control in Gene Therapy Duration: 1 hour and 2 minutes Our panelists will focus on several pertinent topics in rAAV process development including current challenges, technologies for overcoming quality control hurdles, best practices for downstream processing, as well as discuss the current trends and future outlook of this rapidly growing therapeutic frontier. June
Analytical Ultracentrifugation of Carbon Nanotubes Duration: 1 hour 21 minutes 26 seconds Sedimentation velocity (SV) experiments on dispersed nanoparticles present an effective means for determining the hard-to-evaluate properties of nanoparticles. This webinar by Dr. Jeffrey Fagan focuses on leveraging the capabilities of SV methods for characterizing single-wall carbon nanotubes (SWCNTs). Results detailing the use of density contrast techniques on the characterization of the interfacial layer on specific SWCNT species demonstrate the power of analytical ultracentrifugation to resolve this interfacial layer. Dr. Jeffrey Fagan is from the National Institute of Standards and Technology and discusses the analytical ultracentrifugation of single-wall carbon nanotubes, as well as provides background information to apply to other nanoparticles. Dr. Fagan begins with an introduction to analytical ultracentrifugation and a quick explanation of single-wall carbon nanotubes. He discusses what we can characterize with the AUC technique, problems and pitfalls we might encounter, and a discussion about how those pitfalls can differ for different nanoparticles. Lastly, he provides two technical examples using the AUC measurement technique on single-wall carbon nanotubes. May English
Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry Duration: 1 hour 1 minute 3 seconds Beckman Coulter and 3D Biometrix cover topics including why culture cells in 3D, creating and feeding 3D cell cultures in hanging drop plates; reasons to automate 3D culture including examples of compound screening (flow cytometry & high content imaging) as well as automating a full screen. May
Analytical Methods to Measure Empty and Full AAV Particles Duration: 50 minutes 38 seconds Review around biophysical characterizing techniques and a focus on the use of analytical ultracentrifugation (AUC) for measuring empty and full AAV particles May English
Automated Assays For Protein Engineering, In Vitro And In Vivo, By Dr. Daniela Quaglia Duration: 59 minutes 1 seconds Educational webinar covering in vitro and in vivo examples of protein engineering: automation of in vivo and in vitro screening large libraries of enzyme variants. May
Applications of Counterflow Centrifugal Elutriation CCE Duration: 40 minutes Applications of Counterflow Centrifugal Elutriation CCE and the history and principle behind it May English
Automated High-Throughput and High-Content Analysis by Flow Cytometry Duration: 55 minutes 53 seconds Science of Flow Cytometry, Part 2. May
Using Data to Drive Automated Screening and Effective Reporting Duration: 52 minutes 22 seconds Learn how to organize your data to drive results through your assay (miRNA screen) Includes summary of data management tools and data workflow cycle. May
Automating Continuous Cell Culture by Dr. Oliver Gassmann Duration: 42 minutes 20 seconds Learn how continuous cell culture can minimize tedious tasks associated with batch culture, best practices for keeping cells alive in an in vitro environment and how long-term processes can be streamlined with robust planning software. May
Exosome Biogenesis and the Budding of Proteins and Viruses Duration: 1 hour 3 minutes 31 seconds Various models of exosome biogenesis have been proposed. The field however, lacks the robust mechanistic studies needed to obtain a molecular understanding of vesicle secretion. Learn how one lab has taken a cargo-based approach in which the team focuses on the cis-acting signals necessary and sufficient for the budding of specific proteins. Learn from Stephen J Gould why his work supports the hypothesis that the plasma membrane is a major site of exosome budding. May English
High-Performance Exosome Purification and Characterization via automated Density Gradient Duration: 1 hour 19 seconds Rapid, accurate exosome purification and sizing with density gradient, ultracentrifugation and dynamic light scattering by Joshua T. Robinson. May English
Exploring Exosomes and the Tumor Microenvironment Duration: 1 hour 30 minutes 54 seconds Drs. David Lyden and Dr. Thomas Kislinger cover the topic of exosomes and the tumor microenvironment. May English
Fast Cost-Effective High Throughput Solutions for DNA Assembly Duration: 45:44 Fast Cost-Effective High Throughput Solutions for DNA Assembly March
Exploring the Stoichiometry of Macromolecular Complexes Using Multi-Signal Sedimentation Velocity Analytical Ultracentrifugation Duration: 1 hour 14 minutes 43 seconds This webinar by Dr. Chad Brautigam covers the stoichiometry of macromolecule complexes by multi-signal sedimentation velocity analytical ultracentrifugation. May English
Duration: xx minutes (x Videos at x minutes each) March Russian
Extracellular Vesicle Isolation by Flow Cytometric Sorting and Characterization by Analytical Ultra-Centrifugation and Dynamic Light Scatter Duration: 53 minutes 24 seconds This presentation covers extracellular vesicle isolation via flow cytometric sorting and characterization by AUC and dynamic light scatter. May English
Fluorescent amplification for next generation sequencing (FA-NGS) library preparation: A Streamlined Workflow to Improve NGS Quality Control Testing Duration: 26 minutes This webinar will discuss a streamlined library preparation method for next-generation sequencing (NGS) that improves quality control testing capability while reducing the total number of steps compared to conventional multiplexed library workflows. March
Extracellular Vesicles Delivery and RNA Translation Duration: 1 hour 5 minutes 38 seconds This webinar by Charles Lai, PhD covers visualization and tracking for extracellular delivery and RNA translation using multiplexed reporters. May English
Fully Automated RNA Library Preparation for Sequencing Respiratory Viruses Duration: 31 minutes 12 seconds In this webinar, we describe automation of the Illumina RNA Prep with Enrichment (L) Tagmentation kit using the Illumina Respiratory Virus Oligos Panel v2 on the Biomek i7 Hybrid Automated Workstation. We demonstrated/validated the method using SARS-CoV-2 positive samples collected at the Berlin Institute of Health, Berlin, DEU. Our sequencing data shows that the automated method enables comprehensive profiling of viral genome at high throughput, with minimal hands-on time. March
Advanced Flow Cytometric Analysis of Human T-Cell Memory Subsets Duration: 58 minutes 24 seconds Multi-color flow cytometry is a powerful tool to analyze the highly heterogeneous human T cell compartment May
Goldilocks & the Three Cells: The Art of Monitoring & Managing Cell Cultures Duration: 37 minutes 36 seconds Too acidic? Overly alkaline? Or just right? Culturing cells is a subtle, dynamic process that requires constant monitoring and adjustment to maintain a “biological Goldilocks zone (BGZ).” This zone represents the delicate balance between cells, cell media, reagents and growth conditions. In this webinar, Dr. Lenz explains how cell volume data can be used as a surrogate means of monitoring other aspects of cell viability related to the “BGZ.” In particular, he examines how monitoring cell volume can be helpful for assessing cell activation and proliferation – a critical factor in CAR-T cell research. After concluding his remarks, Dr. Lenz participates in a brief but informative Q&A with webinar attendees. (Total time: 37:35) March English
Flow Cytometry Data Analysis in a Flash Duration: 52 minutes 34 seconds An educational webinar on flow cytometry data analysis and how to overcome the analysis burden without a team of bio-statisticians at your disposal May
ICH Q2 Validating a TOC Analyser with the QbD1200 Duration: 27 minutes, 10 seconds Hear Tony Harrison discuss validating a pharmaceutical grade TOC laboratory analyzer to the International Committee on Harmonization procedure ICH Q2. ICH Q2 contains guidance on how to ensure that a TOC analyzer is fit for purpose and for providing batch release data. November English
Gallios Flow Cytometer Forward Angle Light Scatter Innovation Duration: 50 minutes 19 seconds In flow cytometry, the FALS (Forward Angle Light Scatter) detector collects scattered light from a particle that intersects with a laser and delivers information roughly proportional to the size of the particle. Learn more about the unprecedented detection capabilities of the Gallios flow cytometer. May
Cleanroom Routine Environmental Monitoring & Classification Duration: 28 minutes The various GMP guidelines and International ISO standards around GMP cleanrooms are complex and often appear to give conflicting advice, leading to confusion and sometimes incorrect interpretation. In the case of Routine Environmental Monitoring, there is very little prescriptive advice and this lack of direct guidance leaves users struggling to know what to do and the temptation is to either create over-burdensome monitoring programs or to try to simply use the same monitoring plan as is used for classification. Both are incorrect. This webinar discusses the differences between GMP Cleanroom Classification and Routine Environmental Monitoring and explains how Beckman Coulter can help. September
Cytobank Bootcamp Session #6 Single Cell Data Duration: 1 hour 1 minute 26 seconds Apply machine learning algorithms to non-cytometry data. Learn how to analyze other types of single-cell data, including CITE-seq and Single-cell RNA-seq data. April
Cytobank Bootcamp Session #4 FlowSOM Duration: 59 minutes 31 seconds This session will take you through the FlowSOM algorithm; how to set it up, when to use it and combining FlowSOM with viSNE. April
Cytobank Bootcamp Session #1 Introduction to Cytobank Duration: 35 minutes Introduction to the cloud-based Cytobank platform and its machine learning algorithms. April
Cellular Analysis Using the Coulter Principle Duration: 13 minutes 47 seconds Overview of the Coulter Principle, importance of changes in cell volume, overview of basic cell theory (how cells are sized and counted), methods for acquiring count and concentration data. May
Cell Cycle Analysis by Quantitative Imaging Cytometry Duration: 54 minutes 59 seconds Imaging flow cytometry solutions from Beckman Coulter for automated, quantitative high-content, high-throughput cell cycle analysis. May
Centrifugal Elutriation - Utility in the Flow Cytometry Laboratory Duration: 1 hour 4 minutes 57 seconds Dr. Peter Lopez will help you understand the utility of centrifugal elutriation in modern flow cytometry labs May English
Contamination Control in the Hydraulic Industry Duration: 51 minutes 36 seconds Rob Fish presents how contamination affects hydraulics and what you can do about it. April English
Data Insights for Automated Liquid Handling Duration: 14 minutes 40 seconds This webinar covers requirements for successful experiments, equipment and software to effectively enable data collection and elements involved in making a data plan to support data workflow in the lab. May
Analysis of Cell Biochemical Processes from First Principles to Cytometry Duration: 1 hour 3 minutes 9 seconds Cell cycle progression/biochemical processes. Analysis by flow cytometry. May
ACFTD Discontinuance and the HIAC 8011+ and HIAC PODS+ Duration: 41 minutes, 55 seconds Air Cleaner Fine Test Dust (ACFTD) was used by the hydraulics industry as a calibration medium for petroleum based liquid particle counters for many years and served as the basis for generating NAS 1638 and ISO 4402 cleanliness codes. Find out what to do now that ACFTD has been discontinued. Hear Bill F. Bars, Senior Applications Scientist, discuss ACFTD discontinuance in regards to the HIAC 8011+ and HIAC PODS+ liquid particle counters. October English
Analysis of Particle Size Distributions by Analytical Ultracentrifugation Duration: 1 hour 2 minutes 22 seconds Helmut Cölfen discusses and particle size distributions by analytical ultracentrifugation. May English
Achieving Cell-Free Gene Expression with An Acoustic Liquid Handler Duration: 46 minutes and 34 seconds This webinar is part one of a two-part series on abstract cell-free expression. March
Analytical Ultracentrifugation For Structural Analysis - Proteins and Macromolecular Complexes Duration: 1 hour 21 minutes 9 seconds The analytical ultracentrifugation (AUC) technique is presented as a highly effective method for characterizing the structural aspects of macromolecules and as a quantitative technique that provides access to detailed thermodynamic characterization of a system under study. Also learn how AUC enables study of conformational changes and complex formation in physiologically relevant buffers. Dr. Andy Herr provides a great overview of analytical ultracentrifugation (AUC). He discusses basic theory of AUC, sedimentation velocity, sedimentation equilibrium, and more. May English
Laser Cytometry in Biomedical Analysis Duration: 58 minutes 19 seconds Image cytometry (also termed laser scanning cytometry) represents a unique hybrid technology between flow cytometry and traditional fluorescent microscopy. Learn more about the science and vast biomedical applications of quantitative analytical cytology using laser-activated detection. May
Cleanrooms: Controlling Contamination, Setting Alerts & Actions, Considerations of Removal Efficiency Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on September 29, 2020, featuring Joe Gecsey, retired from Beckman Coulter Life Sciences. April
Leveraging the Value of Automated High-Content Screening Duration: 13 minutes 34 seconds Learn how the ImageXpress^® Micro XLS high-content screening system and MetaXpress Software from Molecular Devices can be used to quickly analyze cells, processing 200,000 wells a day. The system is suitable for a range of sample types, beads, colonies, cells, tissue, whole animal and macrostructures. Originally presented at SLAS. May
Microvesicle Detection and Cell Sorting Duration: 57 minutes 11 seconds Webinar presented by Vasilis Toxavidis, MChS, HCPR Resource Director, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute and John Tigges, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute. May
GMP Cleanroom Routine Environmental Monitoring & 21 CFR Part 11 Data Integrity Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on September 30, 2020, featuring Tony Harrison of Beckman Coulter Life Sciences. October
Monitoring Signal Transduction Pathways in Human Disease Duration: 54 minutes 46 seconds The availability of antibodies specifically reactive with phospho-epitopes characteristic of activated signaling proteins provides specific probes that can be used to monitor multiple signal transduction pathways simultaneously. However, successful use of these probes to intracellular targets has required the development of cell fixation and permeabilization techniques that preserve phospho-epitopes, plus cellular light scatter properties, plus cell surface CD molecules. May
Particle Monitoring Systems for Isolator / RABS Filling Lines and 503B Compounding Facilities Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on October 1, 2020, featuring John Wallingford of Pharmagraph. October
Multi-Color Solution for Flow Cytometry Duration: 56 minutes 49 seconds Webinar. Empower your multicolor panel design with tools and techniques from Beckman Coulter. May
Multi-Sizing your Multi-Color for Panel Design Duration: 55 minutes 9 seconds Multi-parametric flow analysis provides tool for dissecting complex cell populations, identifying underlying mechanisms of disease and increasing test efficiencies. Optimal design critical for valid results. May
Measuring Molecular Interactions by Multi-Wavelength AUC Duration: 1 Hour 4 minutes 21 Seconds In this webinar, Dr. Demeler will provide an introduction into this new methodology, its computational challenges, and explain its benefits for the investigation of biopolymer interactions in the solution phase. June
Combined Use of Multiple Particle Characterization Technologies to Evaluate Targeted Liposomal Formulations Duration: 1 hour 6 minutes 46 seconds Multiple particle characterization technologies for evaluating targeted liposomal formulations webinar by Melvin E Klegerman. May English
On the Importance of Monitoring Both Transfection and Transduction Efficiencies in Cell Therapy Development Duration: xx minutes (x Videos at x minutes each) April
Optimizing Quality Control Electronic Records for 21 CFR Part 11 Compliance Duration: 45 minutes 58 seconds In this video, Beckman Coulter Product Manager Tony Harrison covers quality control records and 21 CFR Part 11, manual and electronic SOPs, final product QC, cleanroom environmental monitoring records and QC instrumentation electronic records. February English
Next Generation Polymer Dyes: Enhance your multicolor flow cytometry panels Duration: 57 minutes Polymer dyes are now common tools used to design multicolor flow cytometry panels, however, many existing technologies do have drawbacks. In this session, Lucille Lassalle and Brice Ezzouaouy will introduce SuperNova Dyes, a new generation of polymer dyes designed to deliver ideal brightness, minimal non-specific staining and an optimal staining index. Learn about the unique properties of SuperNova Dyes and how they might help improve your flow cytometry panels, and review staining data, comparing SuperNova Dyes to other polymer dyes. November English
Particle Size Characterization by Laser Diffraction Analysis in Geoscience and Soil Science Duration: 56 minutes 39 seconds Application of particle size characterization in the field of geoscience and soil science. Includes several case studies, discussion of preparation and treatment of materials prior to measurement and importance of subpopulations in wide particle size distributions. Dr. Björn Machalett gives this webinar. May English
Particle Size Distribution for Cement using Laser Diffraction Duration: 48 minutes 2 seconds Importance of particle sizing in cement production. Using laser diffraction. Not all laser diffraction instruments are equal. Webinar presented by Edward Hoff. May English
Q&A Panel discussion, LSUG Lab and Pharma Water speakers Duration: xx minutes (x Videos at x minutes each) July
Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge Duration: 55 minutes 52 seconds Webinar covers physical and chemical characterization of nanoparticle constructs using analytical ultracentrifugation. Webinar is presented by Osman M Bakr from King Abdullah University of Science and Technology. May English
Total Organic Carbon Analysis in the new ASTM E3106 Cleaning Standard Duration: xx minutes (x Videos at x minutes each) July
Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression Duration: 50 minutes 14 seconds Proteomics analysis of tumor microenvironment focused on primary fibroblast-derived exosomes in oral cancer progression presented by Simone Principe from Princess Margaret Cancer Center University Health Network. May English
Real-Time Detection of Bioburden & Biofilm in Water Systems Duration: xx minutes (x Videos at x minutes each) July
Quantifying Protein Aggregates by Sedimentation Velocity Duration: 51 minutes 28 seconds Webinar covering protein aggregate quantification by sedimentation velocity by Michael Stoner PhD of Amgen - PART I. AUC instrumentation & protein aggregate quantification; PART II. Size exclusion chromatography vs sedimentation velocity; PART III. Simulation as a tool for understanding results. May English
ICH Q2 Validation of On-line TOC Analyzers Duration: 23 minutes 59 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses the validation of on-line TOC analyzers for product release testing using ICH Q2. January English
Duration: xx minutes (x Videos at x minutes each) February Russian
Identifying and Isolating Stem Cells Through High-Speed Cell Sorting Duration: 54 minutes 48 seconds Webinar. A discussion of stem cells covering range of topics and cell types from E. Michael Meyer. May English
New Strategies to Improve Your CE-SDS Results: A Data-driven Perspective Duration: 56 minutes 3 seconds This webinar presents new strategies for improving your CD-SDS results including bioproduct analytical testing and a Biomek dilution program. This webinar is presented by Kevin Overstreet at Eli Lilly. May English
New Automation Strategies For Improving Sample Prep - The Analytical Laboratory Duration: 9 minutes 46 seconds This presentation by Michael Kowalski at Beckman Coulter Life Sciences covers automation of capillary electrophoresis and mass spectrometry workflows for the analytical laboratory. Learn how the Biomek 4000 Workstation enables accurate sample prep, essential for downstream applications. May English
Leveraging acoustic and tip-based liquid handling to increase SARS-CoV-2 sequencing throughput 42 minutes 48 seconds In this webinar recording, Dr. Eric Chow from UCSF explains how the ideal protocol requires a low-cost, high-throughput and simple workflow that is compatible with a wide variety of sequencing instruments. February
Isolation and Characterization of Exosomes and Ectosomes Duration: 1 hour 12 minutes 46 seconds Presentation from Suresh Mathivanan at La Trobe University covers practical insights and experience relating to exosome and ectosome isolation & characterization. May English
Isolation of Extracellular Vesicles: Latest Advances and Challenges Duration: 58 minutes 30 seconds A webinar from Winston Patrick Kuo on advances and challenges in isolating extracellular (EV) vesicles. He highlights the need for streamlined, reliable and reproducible EV isolation for downstream studies. May English
Advanced Process Quality Control and Outlier Detection with Discrete Particle Analysis Duration: 47 minutes 29 seconds Avanced process quality control and outlier detection with discrete particle analysis.Covers basic principles, the Coulter Principle and chemical/material applications. May English
Particle Counters Must Now be Calibrated With ISO 21501-4 Duration: 1 hour 2 minutes 56 seconds Overview on calibrating particle counters to 21501-4. May English
Nano-Emulsion Formulation and Characterization Life Science and Industrial Markets Duration: xx minutes (x Videos at x minutes each) This video was a webinar titled "Nano-Emulsion Formulation and Characterization Life Science and Industrial Markets" that was presented on May 27, 2020 featuring featuring John Costello, Ph.D. Edgard Martinez Derek C. Lenz, Ph.D. July
Particle Size and Associated Sedimentary Processes on Wetland Gain and Loss in the Mississippi River Delta Duration: 1 hour 3 minutes 38 seconds Influence of particle size and associated sedimentary processes on wetland gain and loss in the Mississippi River Delta. This webinar is presented by Alexander S Kolker at Louisiana Unviersities Marine Consortium. May English
Cross-talk and Developmental Programs - A Key to Translational Stem Cell Biology Duration: 1 hour 31 minutes 13 seconds Cellular signaling mediated by extracellular membrane vesicles in the application of stem cells as therapeutics. May
Advances in Sedimentation Analysis by Dr. Borries Demeler Duration: 1 hour 8 minutes 46 seconds This presentation covers advances in sedimentation velocity (SV) analysis including methods for accurately characterizing heterogeneous systems at high resolution; approaches to extract rich information from SV experiments and techniques to measure the strength of macromolecular interactions with discrete binding models to whole boundary SV experiments in analytical ultracentrifugation. April English
Automated Alternative to the Hanging Drop Method of Stem Cell Differentiation Duration: 55 minutes 53 seconds May
21 CFR Part 11 Data Integrity for Online TOC Instruments Duration: 34 minutes 39 seconds Beckman Coulter Life Sciences sponsors a video on 21 CFR Part 11 data integrity for online TOC instrumentation, presented by Tony Harrison September English
Large Scale Purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation Duration: 1 hour 1 minutes 45 seconds Webinar from Daniel Jasinski covers RNA nanotechnology in cancer therapy. RNA/RNA-based nanoparticle purification by ultracentrifugation including current technologies, different methods of ultracentrifugation, why large quantities of RNA are needed, methods for large-scale RNA purification. May English
ICH Q2 Validation of Analytical Procedures for Pharmaceutical TOC Analyzers Duration: 31 minutes The tripartite International Conference on Harmonization (ICH) Q2 guide on validation of analytical procedures is not new, but it can give very good advice when validating laboratory Total Organic Carbon (TOC) analyzers for pharmaceutical use, especially when a user is considering changing analyzer brands or TOC analysis technologies. This webinar discusses how ICH Q2 can be applied to TOC analyzers to ensure they are suitable for pharmaceutical applications. March
Is Immunotherapy Living up to its Promise? Duration: 1 hour 24 minutes 9 seconds Watch this webinar on the advancements and performance of immunotherapy, presented by Jill O'Donnell-Tormey and Alex Y. Huang May English
Initial Evaluation of the ClearLLab 10C System in the Immunophenotyping of Leukemia and Non Hodgkin Lymphoma Duration: 42 minutes 59 seconds In this webinar understand the process for routine cocktail selection and preparation, describe the key concepts in the ClearLLab 10 color system design, demonstrate using case studies the applicability of ClearLLab reagents and evaluate the results of the clinical accuracy study. April
Hematopoietic Bone Marrow Cell Sorting without Compromise Duration: 52 minutes 25 seconds Flow cytometry analysis and sorting are valuable techniques for studying distinct hematopoietic bone marrow populations. Webinar covers identification, isolation and purification of hematopoietic stem cells. May
Kaluza Batch Analysis Tutorial with Dr. David Onion Duration: 7 minutes 42 seconds In this Kaluza data analysis video the batch analysis gets explored. In a nutshell batch analysis allows you to use any, protocol file, composite, or Kaluza analysis file as a template to perform analysis on as many files as you like. This would become really useful if you were compiling reports, perhaps you’re writing a paper and you wanted to get all your data together and make sure it is analyzed in exactly the same way. November
How Stem Cells Speak with Immune Cells Duration: 1 hour 8 minutes 33 seconds Watch this webinar from Stefan Pluchino on how stem cells signal to the host immune system May English
Recent Advances in Immunotherapy: Directing Cells to Address Disease Duration: 1 hour 10 minutes 2 seconds Watch this webinar on the recent advances in immunotherapy with a focus on directing cells to address disease, presented by Leena Gandhi MD PhD May English
Diamond-Based Nanomedicine for Enhanced Cancer Treatment and Imaging Duration: 58 minutes 12 seconds This webinar covers the unique attributes of diamond-based nanoparticles and why they are effective when imaging for cancer and drug delivery as well as their in-vitro and in-vivo applications. May
Duration: xx minutes (x Videos at x minutes each) April Russian
Diversity of Cancer-Derived Extracellular Vesicles Duration: 59 minutes 59 seconds This webinar from Dr. Dolores Di Vizio covers extracellular vesicle heterogeneity, large oncosomes and potentials for biomarker development. May English
Diversity of Extracellular Vesicles and Their Cargo in Cell-To-Cell Communication Duration: 1 hour 2 minutes 56 seconds Dr. Jan Lötvall discusses the study of extracellular vesicles and their relevance for cell-to-cell communication and how they have been implicated in several ways in disease progression. Understand the wide diversity of extracellular vesicles, with diverse morphology according to electron microscopy studies and difference in RNA and protein cargo according to bioinformatics analyses. May English
Emitting Dye for Violet Laser Excitation with Krome Orange Duration: 29 minutes 50 seconds Krome Orange dye conjugates can be used on any flow cytometer equipped with violet excitation and appropriate emission filters. Data presented using Krome Orange conjugates of anti-human CD4, CD19 and CD45 in multicolor applications, including side scatter/CD45 gating and a 6-plus color stain. Krome Orange dye provides optimized second organic fluorochrome for violet excitation, enabling 10-color applications on the Gallios / Navios flow cytometer systems. May
European Pharmacopoeia EP2.2.44 Total Organic Carbon Duration: 28 minutes 41 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses European Pharmacopoeia and complete TOC oxidation for PW and WFI. January English
Evolution in the Manufacturing of Cellular Therapies Duration: xx minutes (x Videos at x minutes each) Lessons learned and current solutions Immunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy, the result is an expanded population of T cells primed to recognize and eradicate malignant tumor cells that would otherwise escape immune detection. The webinar will discuss how cellular therapies have evolved, lessons learned through the evolution and current solutions available today. Learning Objectives: Commercialization of manufacturing- preparing a CAR Garage, lessons learned and how does it impact the patient. Automated functional testing- fully integrated unit operations taking the art out of science! January
Cytobank Bootcamp Session #3 viSNE Duration: 60 minutes This webinar demonstrates how to set up viSNE, optimize it and interpret the results within the Cytobank platform. April
Cytobank Bootcamp Session #2 Data Management Duration: 60 minutes This session provides specifics on data security, data pre-processing, exporting statistics, and figure generation within the Cytobank platform April
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Cytobank Bootcamp Session #5 Biomarker discovery with CITRUS Duration: 59 minutes 29 seconds Join us in learning how to utilize CITRUS algorithm for identification of differences between experimental groups April
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Duration: xx minutes (x Videos at x minutes each) June Russian
Pharmaceutical Water Production, Richard Jarrett, Evoqua Water Technologies Duration: xx minutes (x Videos at x minutes each) July
Meeting Global TOC and Conductivity Pharmacopeia Compliance while using ALCOA Requirements to Protect Data Integrity Duration: xx minutes (x Videos at x minutes each) This video was part of the annual LSUG Laboratory and Pharma Water Production event on June 23, 2020. Featuring Paul Farrell of Beckman Coulter Life Sciences July
Validation of Growth Direct to Perform Pharmaceutical Water Bioburden Analysis Duration: xx minutes (x Videos at x minutes each) This video was part of the annual LSUG Laboratory and Pharma Water Production event on June 23, 2020. Featuring Susan Schilling of Rapid Micro Biosystems July
Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses Using Analytical Ultracentrifugation Duration: 1 hour 2 minutes 35 seconds Live broadcast covering applications of analytical ultracentrifugation (AUC). May English
Rethinking Data Analysis for Flow Cytometry with Kaluza 1.1 Software Duration: 55 minutes 56 seconds Quickly and efficiently analyze multi-color, multi-parametric high content data generated by today's flow cytometers with revolutionary Kaluza analysis software. May
Predictive power of CITRUS Duration: xx minutes (x Videos at x minutes each) Learn how the power of CITRUS can identify and assign statistical significance to biological signatures that differentiate samples across multiple groups 21.03.1120.FLOW March
Duration: xx minutes (x Videos at x minutes each) April Russian
Sample Prep for MS Duration: 45 minutes 39 seconds This webinar covers automated Biomek solutions for mass spec sample prep. April English
Contemporary Cell Staining and Imaging Tools for Screening Stem Cell-Derived Cardiomyocytes Duration: 59 minutes Webinar presented by Beckman Coulter, Molecular Devices and Cellular Dynamics covers image-based cardiomyocyte assays including a comprehensive toolbox and complete image solution for your image analysis needs. May
Reducing Human Errors in Pharmaceutical Manufacturing Quality Control Duration: 25 minutes 50 seconds Beckman Coulter Life Sciences sponsors a video on reducing human error in pharmaceutical quality control. September
The Art of Sorting for Advancing Cytometry Duration: 55 minutes 27 seconds Learn the basic elements for successful sorting: droplet breakoff, particle detection, sort decisions/delay, droplet charging and deflection. May
Scaling-Up Exosomes and Other Extracellular Vesicles Duration: 59 minutes In this webinar, Derek C. Lenz, Ph.D. covers ways to take your EV production to the next level. August
Take the Risk out of Rotations Understanding and Implementing BioSafety Solutions in Centrifugation Duration: 57 minutes 20 seconds Watch Dr. Derek C. Lenz's webinar on Take the Risk out of Rotations Understanding and Implementing BioSafety Solutions in Centrifugation April
Testing Vaccines Final Form Dose to USP<787> Subvisible Particulate Matter Duration: 23 minutes A presentation on the challenges that fully implementing USP<787> presents to liquid particle counters with inherently large tare volumes, poor sample-to-sample repeatability with such low sample volumes and inability to precisely deliver small volumes. December
The Future of Liquid Handling Automation has Arrived Duration: 59 minutes 2 seconds First webinar in a three-part series introducing the new Biomek i-Series Automated Workstations. Two new liquid handlers designed to enable continuous innovation for tackling the ever-changing demands of life science research in mid- to high-throughput labs. Meet the product development team and learn more about new solutions. Q&A included. Additional webinars cover how i-Series solutions can accelerate a range of applications. May
The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems Duration: 1 hour and 10 minutes September
The Power of Automated Assay Optimization Duration: 39 minutes 11 seconds This webinar addresses the topic of automated assay optimization - what it is, why do it and benefits realized. May
Transferring Cell Counting Methods: Best Practices Duration: xx minutes (x Videos at x minutes each) April
The Role of Exosomes in Inflammatory Disease - Pathogenesis and Treatment Duration: 1 hour 19 minutes 41 seconds This webinar covers the biology of exosomes and how they are involved in inflammatory diseases. Exosomes as biomarkers and therapeutic agents. May English
Understanding the How and the Why: Biosafety in Centrifugation Duration: 59 minutes This webinar will address potential gaps, review proper use and maintenance of centrifuges, rotors, and labware with a focus on BioSafety (42 CFR part 73). The intent is to provide information to assist with utilizing centrifugation in a more productive and safe manner. October
The Science of Flow Cytometry Part 1 Duration: 53 minutes 44 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 1. May
qPCR Webinar: Scalable Workflows for Viral RNA Extraction and Reaction Setup Duration: 40 minutes 18 seconds Watch the collaboration between Beckman Coulter Life Sciences and IDT for the solutions to qPCR sample prep, featuring viral RNA extraction reagent kits. August
The Science of Flow Cytometry Part 2 Duration: 55 minutes 53 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 2. May
Seminar: Advanced Sensitivity and Resolution in Flow Cytometry through Innovation Duration: 1 hour 21 minutes 46 seconds J. Paul Robinson from Purdue University describes the innovations borrowed from the telecommunications industry that are being applied to flow cytometry. The unique collection of technologies are fueling the miniaturization of flow cytometry instruments while increasing the sensitivity and resolution of detected particles. April
Environmental Cleanroom Monitoring & 21 CFR Part 11 Data Integrity Duration: 33 minutes 20 seconds This webinar was presented by Beckman Coulter Life Science' Tony Harrison on July 27 2020. May English
Three Distinct Analytical Ultracentrifugation Methods for Virus and Viral Vector Characterizations Duration: 33 minutes 5 seconds Sedimentation velocity analytical ultracentrifugation (SV-AUC) is considered the gold standard method for the size distribution analysis of viral vectors for gene therapy, but you have other orthogonal AUC methods to choose from too, including band sedimentation AUC (BS-AUC) and density gradient equilibrium AUC (DGE-AUC). September
Webinar: NanoGBS—A Miniaturized Procedure for Genotyping by Sequencing Library Preparation Duration: 44 minutes and 20 seconds High-throughput reduced-representation sequencing (RRS)-based genotyping methods, such as genotyping-by-sequencing (GBS), have provided attractive genotyping solutions in numerous species. In this webinar, Davoud Torkamaneh, PhD, assistant professor at Université Laval, will discuss NanoGBS, a miniaturized, eco-friendly method for GBS library construction. March
Changes to USP <643> Total Organic Carbon for Pharmaceutical Grade Waters Duration: xx minutes (x Videos at x minutes each) A revised version of the USP chapter on Total Organic Carbon (TOC) USP<643> was published recently and will become official on 1st May 2021. This paper gives an overview of this new USP chapter and discusses the reasoning behind the difference in the System Suitability Test materials called for in USP<643> and those in the Japanese JP16. Learning Objectives: Learn about the revised USP chapter on Total Organic Carbon (TOC) USP<643> which will become official on 1st May 2021 Learn about the System Suitability Test in USP<643> Learn the reason why Japanese Pharmacopoeia calls for different System Suitability Testing materials to USP May English
Understanding the Role and Benefits of Centrifugation in Cell Harvest and Separation Duration: 36 minutes In this webinar we will provide an overview of technology for primary recovery, considerations for choosing equipment, and tips and tricks to improve your process. March
Clinical Flow Cytometry User Group Meeting Duration: 2 hours 00 minutes Learning Lesson 1 – The Healthy Immune System (Dr. Lisa Holey, Clinical Solutions Manager, Beckman Coulter Life Sciences) Learning Lesson 2 – How to Identify Aberrant Cells (Sandra Hernandez, Product Manager, Beckman Coulter Life Sciences) Technical Session – Plasma Cell Testing for Myeloma MRD Analysis (Mike Sutter, Technical Specialist, Pathology Consultants) December English
Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy Duration: 46 minutes 34 seconds Understand the role viral vectors play in modern gene research and how ultracentrifugation is used to produce these key delivery systems May English
Cytobank Webinar - CITRUS in Practice with Dr. Anna Belkina Duration: 57 minutes 29 seconds Special guest Dr. Anna Belkina, Associate Director of the Flow Cytometry Core at Boston University, outlines her approach and results, as published in Frontiers in Immunology: “Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging”. See how the CITRUS algorithm can perform robust statistical analysis without requiring code, and understand how CITRUS can be applied to reveal unexpected findings from your dataset with the Cytobank platform. November
GMP Cleanroom Routine Environmental Monitoring & 21 CFR Part 11 Data Integrity Duration: xx minutes (x Videos at x minutes each) August
Introduction to the New USP <787>: Subvisible Particulate Matter in Therapeutic Protein Injections Duration: 1 hour 6 minutes 30 seconds An introduction to USP <787>: Purpose and differences between <787> and <788>, visible vs subvisible particles, methods and technology. May
Duration: xx minutes (x Videos at x minutes each) April Russian
Cytometry data sharing platform for collaborative multi-centric data analysis Duration: xx minutes (x Videos at x minutes each) In this webinar, Dr. LUCHE showcases the ease of data management and illustration design in the Cytobank platform, allowing fast interrogation of multi-group multi-sample datasets. April
Overcoming the Hurdles of Density Gradient Ultracentrifugation for Optimized Gene Therapy Purification Workflows Duration: 51 minutes 6 seconds Learn about the various types of density gradients techniques, how they are used, and how to get started as well as how to design and optimize a density gradient ultracentrifugation workflow, with AAV and plasmid DNA purification as examples. March English
Looking Under the Hood: Getting Started with the Optima AUC Duration: 56 minutes 5 seconds In the webinar we discuss the fundamentals of analytical ultracentrifugation and look at a few sample applications. October
Webinar: An Intro to Characterization of Biomolecules Using AUC Duration: 60 minutes 13 seconds Analytical Ultracentrifugation (AUC) is one of the most powerful biophysical tools used today for the characterization of biological samples ranging from small drug molecules to intact viruses, vesicles and microparticles October
Characterizing Viral Vector Fullness in Density Gradient Separations Duration: 30 minutes Known as density gradient equilibrium analytical ultracentrifugation (DGE-AUC), it’s a simplified method that provides high-resolution benefits along with numerous advantages over the current gold standard sedimentation velocity AUC. Watch webinar to learn more. July
Machine Learning Assisted Population Identification Duration: xx minutes (x Videos at x minutes each) Leverage machine learning to identify novel cell populations and integrate single-cell technologies. Describes the application of a pipeline data analysis to increase consistency for multisite studies applied to overcome challenges due to CD4+ T cell plasticity. May
The Revised ISO 14644-1 Changes Classification and Monitoring Methods Duration: 1 hour 16 minutes 55 seconds ISO 14644-1: Impacts on classification methods and monitoring strategies presented by Joe Gecsey. February

Cell-Free Technology and Acoustic Liquid Handling Are Helping Tierra Disrupt Natural Product Discovery

Duration: 1 hour 28 seconds If you want to disrupt the natural products market, try combining acoustic liquid handling technology with advances in cell-free approaches. In this webinar, Zachary Sun, CEO of Tierra Biosciences (formerly Synvitrobio), shares how his company is doing just that using the Echo Liquid Handler.

March

English

An End-to-End Automated Workflow for High-Throughput SARS-Cov-2 Sequencing and Surveillance

Duration: 59 minutes 56 seconds In this webinar, we highlight the collaboration between the European Molecular Biology Laboratory (EMBL), New England Biolabs (NEB), and Beckman Coulter Life Sciences to develop an automated high-throughput NGS library prep workflow for SARS-CoV-2 surveillance using the NEBNext ARTIC SARS-CoV-2 Library Prep Kit (Illumina) and the Biomek i7 Hybrid NGS Workstation.

March

Cell Counting & Viability: Faster Results Through Automation

Duration: xx minutes (x Videos at x minutes each)

You will learn how the Vi-CELL BLU automates the entire analysis process – sample aspiration, trypan blue mixing, image analysis and instrument cleaning – to revolutionize the speed, reliability and reproducibility of results, and provides critical information manual cell counting methods simply cannot offer.

Speaker: Uwe Killemann
Field Marketing Manager Europe
Beckman Coulter Life Sciences

November

Avoid Pitfalls When Automating Cell Viability Counting for Biopharmaceutical Quality Control

Duration: 48 minutes 17 seconds

This educational webinar covers various modern automated cell counter technology, common pitfalls and how to avoid them. Includes discussion of the atuomated Trypan Blue cell counting method on the Vi-CELL XR.

May

English

Changes to USP <1788>: Determination of Subvisible Particle Matter from the HIAC and Coulter Counters

Duration: xx minutes (x Videos at x minutes each)

A revised version of the USP chapter on Subvisible Particulate Matter USP<1788> became official on 1st May 2021. USP<1788> is meant to expand on the information given in the chapters <787>, <788> and <789> to include for the first time the use of Flow Imaging techniques to provide orthogonal complimentary information to the HIAC high accuracy particle counter used in the compendial Light Obscuration Limit Test.

June

Taking the Tricky Out of Automating NGS Sample Prep

Duration: 14 minutes 30 seconds Presentation addresses challenging tasks in NGS (and other) workflows. Resources, demonstrated methods, instruments and techniques from Beckman Coulter also covered.

May

Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler

Duration: 52 minutes 41 seconds In this webinar, we show how prototyping CRISPR components can be accelerated by combining a cell-free transcription and translation (TXTL) system with an Echo Acoustic Liquid Handler (LH) from Beckman Coulter Life Sciences.

March

Automation-Enabled LC-MS Analysis of Biologics

Duration: 14 minutes 50 seconds This is a webinar discussing the Analysis of Biologics

June

Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler

Duration: 44 minutes and 30 seconds This webinar is part two of a two-part series on abstract cell-free expression.

March

Characterization of Extracellular Vesicles with Nanoscale Flow Cytometry

Duration: 49 minutes 14 seconds How to set up a flow cytometer for nanoparticle analyses

February

Automation of PCR Setup and AMPure XP Purification using the Biomek 4000 Workstation

Duration: 33 minutes 55 seconds This webinar covers PCR Setup and AMPure XP cleanup applications using the Biomek 4000.

May

Characterizing Viruses: From Deadly Pathogens to the Workhorses of Gene Therapy

Duration: 1 hour 3 minutes 6 seconds In this webinar, Dr. Bhattacharya will discuss the role of analytical ultracentrifugation (AUC) in uncovering the biophysics of these therapeutic targets. We will discuss typical case examples, including one where AUC is used to determine the dimerization affinity of SARS-CoV-2 protease.

July

Avoiding the Perils of Hidden Requirements

Duration: 14 minutes 7 seconds This video presentation covers important considerations and sometimes overlooked requirements when selecting an integration partner.

May

Choosing the Right TOC Analyzer for a Pharmaceutical QC Laboratory

Duration: 58 minutes, 9 seconds Hear Tony Harrison discuss the regulations for total organic carbon in pharmaceutical water, the typical measurement technologies that are used by TOC analyzers in pharmaceutical water analysis quality control, and lastly hear the introduction of a lab quality control analyzer that has been optimized for laboratory QC applications.

April

English

Basic Research Signaling Applications

Duration: 55 minutes 39 seconds Basic signaling applications in life sciences research.

May

The Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals

Duration: 1 hour 2 minutes 20 seconds This webinar covers the key attributes of AUC as a highly effective technique for characterizing viral vectors for viral gene therapy delivery systems

May

English

Analytical Ultracentrifugation in the Biopharmaceutical Industry

Duration: 1 hour 4 minutes 34 seconds Dr. Alexander Bepperling focuses on the data analysis tools to achieve high precision when analyzing biopharmaceutical products due to an interest in minor species of about 1-2% usually comprising of the total protein content. He focuses on the data analysis done in SEDFIT. Learn how to set up continuous c(S) distribution analysis as implemented with SEDFIT software for enhanced reproducibility during a study of many batches of one protein. Also covers applications of sedimentation equilibrium (SE) for screening weak interactions and determining detergent binding to proteins.

May

English

Analytical Ultracentrifugation in Nanoparticle Analysis

Duration: 1 hour 1 minutes 43 seconds Joshua Robinson covers the utility of fractionation in the investigation of complex mixtures and polydisperse samples as well as versatility of analytical ultracentrifugation (AUC) for colloid chemistry. He quickly reviews analytical ultracentrifugation (AUC) theory, then discusses deconstructing nano-constructs and how AUC has been used in recent literature to really probe the underlying structure of nano-constructs, nanomaterials. Other topics covered include nanoparticle sample preparation, as well as Beckman Coulter's research and future perspectives.

May

English

Addressing the Challenges of Purification & Quality Control in Gene Therapy

Duration: 1 hour and 2 minutes Our panelists will focus on several pertinent topics in rAAV process development including current challenges, technologies for overcoming quality control hurdles, best practices for downstream processing, as well as discuss the current trends and future outlook of this rapidly growing therapeutic frontier.

June

Analytical Ultracentrifugation of Carbon Nanotubes

Duration: 1 hour 21 minutes 26 seconds Sedimentation velocity (SV) experiments on dispersed nanoparticles present an effective means for determining the hard-to-evaluate properties of nanoparticles. This webinar by Dr. Jeffrey Fagan focuses on leveraging the capabilities of SV methods for characterizing single-wall carbon nanotubes (SWCNTs). Results detailing the use of density contrast techniques on the characterization of the interfacial layer on specific SWCNT species demonstrate the power of analytical ultracentrifugation to resolve this interfacial layer. Dr. Jeffrey Fagan is from the National Institute of Standards and Technology and discusses the analytical ultracentrifugation of single-wall carbon nanotubes, as well as provides background information to apply to other nanoparticles. Dr. Fagan begins with an introduction to analytical ultracentrifugation and a quick explanation of single-wall carbon nanotubes. He discusses what we can characterize with the AUC technique, problems and pitfalls we might encounter, and a discussion about how those pitfalls can differ for different nanoparticles. Lastly, he provides two technical examples using the AUC measurement technique on single-wall carbon nanotubes.

May

English

Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry

Duration: 1 hour 1 minute 3 seconds Beckman Coulter and 3D Biometrix cover topics including why culture cells in 3D, creating and feeding 3D cell cultures in hanging drop plates; reasons to automate 3D culture including examples of compound screening (flow cytometry & high content imaging) as well as automating a full screen.

May

Analytical Methods to Measure Empty and Full AAV Particles

Duration: 50 minutes 38 seconds Review around biophysical characterizing techniques and a focus on the use of analytical ultracentrifugation (AUC) for measuring empty and full AAV particles

May

English

Automated Assays For Protein Engineering, In Vitro And In Vivo, By Dr. Daniela Quaglia

Duration: 59 minutes 1 seconds Educational webinar covering in vitro and in vivo examples of protein engineering: automation of in vivo and in vitro screening large libraries of enzyme variants.

May

Applications of Counterflow Centrifugal Elutriation CCE

Duration: 40 minutes Applications of Counterflow Centrifugal Elutriation CCE and the history and principle behind it

May

English

Automated High-Throughput and High-Content Analysis by Flow Cytometry

Duration: 55 minutes 53 seconds Science of Flow Cytometry, Part 2.

May

Using Data to Drive Automated Screening and Effective Reporting

Duration: 52 minutes 22 seconds Learn how to organize your data to drive results through your assay (miRNA screen) Includes summary of data management tools and data workflow cycle.

May

Automating Continuous Cell Culture by Dr. Oliver Gassmann

Duration: 42 minutes 20 seconds Learn how continuous cell culture can minimize tedious tasks associated with batch culture, best practices for keeping cells alive in an in vitro environment and how long-term processes can be streamlined with robust planning software.

May

Exosome Biogenesis and the Budding of Proteins and Viruses

Duration: 1 hour 3 minutes 31 seconds Various models of exosome biogenesis have been proposed. The field however, lacks the robust mechanistic studies needed to obtain a molecular understanding of vesicle secretion. Learn how one lab has taken a cargo-based approach in which the team focuses on the cis-acting signals necessary and sufficient for the budding of specific proteins. Learn from Stephen J Gould why his work supports the hypothesis that the plasma membrane is a major site of exosome budding.

May

English

High-Performance Exosome Purification and Characterization via automated Density Gradient

Duration: 1 hour 19 seconds Rapid, accurate exosome purification and sizing with density gradient, ultracentrifugation and dynamic light scattering by Joshua T. Robinson.

May

English

Exploring Exosomes and the Tumor Microenvironment

Duration: 1 hour 30 minutes 54 seconds Drs. David Lyden and Dr. Thomas Kislinger cover the topic of exosomes and the tumor microenvironment.

May

English

Fast Cost-Effective High Throughput Solutions for DNA Assembly

Duration: 45:44 Fast Cost-Effective High Throughput Solutions for DNA Assembly

March

Exploring the Stoichiometry of Macromolecular Complexes Using Multi-Signal Sedimentation Velocity Analytical Ultracentrifugation

Duration: 1 hour 14 minutes 43 seconds This webinar by Dr. Chad Brautigam covers the stoichiometry of macromolecule complexes by multi-signal sedimentation velocity analytical ultracentrifugation.

May

English

Duration: xx minutes (x Videos at x minutes each)

March

Russian

Extracellular Vesicle Isolation by Flow Cytometric Sorting and Characterization by Analytical Ultra-Centrifugation and Dynamic Light Scatter

Duration: 53 minutes 24 seconds This presentation covers extracellular vesicle isolation via flow cytometric sorting and characterization by AUC and dynamic light scatter.

May

English

Fluorescent amplification for next generation sequencing (FA-NGS) library preparation: A Streamlined Workflow to Improve NGS Quality Control Testing

Duration: 26 minutes This webinar will discuss a streamlined library preparation method for next-generation sequencing (NGS) that improves quality control testing capability while reducing the total number of steps compared to conventional multiplexed library workflows.

March

Extracellular Vesicles Delivery and RNA Translation

Duration: 1 hour 5 minutes 38 seconds This webinar by Charles Lai, PhD covers visualization and tracking for extracellular delivery and RNA translation using multiplexed reporters.

May

English

Fully Automated RNA Library Preparation for Sequencing Respiratory Viruses

Duration: 31 minutes 12 seconds In this webinar, we describe automation of the Illumina RNA Prep with Enrichment (L) Tagmentation kit using the Illumina Respiratory Virus Oligos Panel v2 on the Biomek i7 Hybrid Automated Workstation. We demonstrated/validated the method using SARS-CoV-2 positive samples collected at the Berlin Institute of Health, Berlin, DEU. Our sequencing data shows that the automated method enables comprehensive profiling of viral genome at high throughput, with minimal hands-on time.

March

Advanced Flow Cytometric Analysis of Human T-Cell Memory Subsets

Duration: 58 minutes 24 seconds Multi-color flow cytometry is a powerful tool to analyze the highly heterogeneous human T cell compartment

May

Goldilocks & the Three Cells: The Art of Monitoring & Managing Cell Cultures

Duration: 37 minutes 36 seconds Too acidic? Overly alkaline? Or just right? Culturing cells is a subtle, dynamic process that requires constant monitoring and adjustment to maintain a “biological Goldilocks zone (BGZ).” This zone represents the delicate balance between cells, cell media, reagents and growth conditions. In this webinar, Dr. Lenz explains how cell volume data can be used as a surrogate means of monitoring other aspects of cell viability related to the “BGZ.” In particular, he examines how monitoring cell volume can be helpful for assessing cell activation and proliferation – a critical factor in CAR-T cell research. After concluding his remarks, Dr. Lenz participates in a brief but informative Q&A with webinar attendees. (Total time: 37:35)

March

English

Flow Cytometry Data Analysis in a Flash

Duration: 52 minutes 34 seconds

An educational webinar on flow cytometry data analysis and how to overcome the analysis burden without a team of bio-statisticians at your disposal

May

ICH Q2 Validating a TOC Analyser with the QbD1200

Duration: 27 minutes, 10 seconds Hear Tony Harrison discuss validating a pharmaceutical grade TOC laboratory analyzer to the International Committee on Harmonization procedure ICH Q2. ICH Q2 contains guidance on how to ensure that a TOC analyzer is fit for purpose and for providing batch release data.

November

English

Gallios Flow Cytometer Forward Angle Light Scatter Innovation

Duration: 50 minutes 19 seconds In flow cytometry, the FALS (Forward Angle Light Scatter) detector collects scattered light from a particle that intersects with a laser and delivers information roughly proportional to the size of the particle. Learn more about the unprecedented detection capabilities of the Gallios flow cytometer.

May

Cleanroom Routine Environmental Monitoring & Classification

Duration: 28 minutes The various GMP guidelines and International ISO standards around GMP cleanrooms are complex and often appear to give conflicting advice, leading to confusion and sometimes incorrect interpretation. In the case of Routine Environmental Monitoring, there is very little prescriptive advice and this lack of direct guidance leaves users struggling to know what to do and the temptation is to either create over-burdensome monitoring programs or to try to simply use the same monitoring plan as is used for classification. Both are incorrect. This webinar discusses the differences between GMP Cleanroom Classification and Routine Environmental Monitoring and explains how Beckman Coulter can help.

September

Cytobank Bootcamp Session #6 Single Cell Data

Duration: 1 hour 1 minute 26 seconds Apply machine learning algorithms to non-cytometry data. Learn how to analyze other types of single-cell data, including CITE-seq and Single-cell RNA-seq data.

April

Cytobank Bootcamp Session #4 FlowSOM

Duration: 59 minutes 31 seconds This session will take you through the FlowSOM algorithm; how to set it up, when to use it and combining FlowSOM with viSNE.

April

Cytobank Bootcamp Session #1 Introduction to Cytobank

Duration: 35 minutes Introduction to the cloud-based Cytobank platform and its machine learning algorithms.

April

Cellular Analysis Using the Coulter Principle

Duration: 13 minutes 47 seconds Overview of the Coulter Principle, importance of changes in cell volume, overview of basic cell theory (how cells are sized and counted), methods for acquiring count and concentration data.

May

Cell Cycle Analysis by Quantitative Imaging Cytometry

Duration: 54 minutes 59 seconds Imaging flow cytometry solutions from Beckman Coulter for automated, quantitative high-content, high-throughput cell cycle analysis.

May

Centrifugal Elutriation - Utility in the Flow Cytometry Laboratory

Duration: 1 hour 4 minutes 57 seconds Dr. Peter Lopez will help you understand the utility of centrifugal elutriation in modern flow cytometry labs

May

English

Contamination Control in the Hydraulic Industry

Duration: 51 minutes 36 seconds Rob Fish presents how contamination affects hydraulics and what you can do about it.

April

English

Data Insights for Automated Liquid Handling

Duration: 14 minutes 40 seconds This webinar covers requirements for successful experiments, equipment and software to effectively enable data collection and elements involved in making a data plan to support data workflow in the lab.

May

Analysis of Cell Biochemical Processes from First Principles to Cytometry

Duration: 1 hour 3 minutes 9 seconds Cell cycle progression/biochemical processes. Analysis by flow cytometry.

May

ACFTD Discontinuance and the HIAC 8011+ and HIAC PODS+

Duration: 41 minutes, 55 seconds Air Cleaner Fine Test Dust (ACFTD) was used by the hydraulics industry as a calibration medium for petroleum based liquid particle counters for many years and served as the basis for generating NAS 1638 and ISO 4402 cleanliness codes. Find out what to do now that ACFTD has been discontinued. Hear Bill F. Bars, Senior Applications Scientist, discuss ACFTD discontinuance in regards to the HIAC 8011+ and HIAC PODS+ liquid particle counters.

October

English

Analysis of Particle Size Distributions by Analytical Ultracentrifugation

Duration: 1 hour 2 minutes 22 seconds Helmut Cölfen discusses and particle size distributions by analytical ultracentrifugation.

May

English

Achieving Cell-Free Gene Expression with An Acoustic Liquid Handler

Duration: 46 minutes and 34 seconds This webinar is part one of a two-part series on abstract cell-free expression.

March

Analytical Ultracentrifugation For Structural Analysis - Proteins and Macromolecular Complexes

Duration: 1 hour 21 minutes 9 seconds The analytical ultracentrifugation (AUC) technique is presented as a highly effective method for characterizing the structural aspects of macromolecules and as a quantitative technique that provides access to detailed thermodynamic characterization of a system under study. Also learn how AUC enables study of conformational changes and complex formation in physiologically relevant buffers. Dr. Andy Herr provides a great overview of analytical ultracentrifugation (AUC). He discusses basic theory of AUC, sedimentation velocity, sedimentation equilibrium, and more.

May

English

Laser Cytometry in Biomedical Analysis

Duration: 58 minutes 19 seconds Image cytometry (also termed laser scanning cytometry) represents a unique hybrid technology between flow cytometry and traditional fluorescent microscopy. Learn more about the science and vast biomedical applications of quantitative analytical cytology using laser-activated detection.

May

Cleanrooms: Controlling Contamination, Setting Alerts & Actions, Considerations of Removal Efficiency

Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on September 29, 2020, featuring Joe Gecsey, retired from Beckman Coulter Life Sciences.

April

Leveraging the Value of Automated High-Content Screening

Duration: 13 minutes 34 seconds Learn how the ImageXpress^® Micro XLS high-content screening system and MetaXpress Software from Molecular Devices can be used to quickly analyze cells, processing 200,000 wells a day. The system is suitable for a range of sample types, beads, colonies, cells, tissue, whole animal and macrostructures. Originally presented at SLAS.

May

Microvesicle Detection and Cell Sorting

Duration: 57 minutes 11 seconds Webinar presented by Vasilis Toxavidis, MChS, HCPR Resource Director, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute and John Tigges, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute.

May

GMP Cleanroom Routine Environmental Monitoring & 21 CFR Part 11 Data Integrity

Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on September 30, 2020, featuring Tony Harrison of Beckman Coulter Life Sciences.

October

Monitoring Signal Transduction Pathways in Human Disease

Duration: 54 minutes 46 seconds The availability of antibodies specifically reactive with phospho-epitopes characteristic of activated signaling proteins provides specific probes that can be used to monitor multiple signal transduction pathways simultaneously. However, successful use of these probes to intracellular targets has required the development of cell fixation and permeabilization techniques that preserve phospho-epitopes, plus cellular light scatter properties, plus cell surface CD molecules.

May

Particle Monitoring Systems for Isolator / RABS Filling Lines and 503B Compounding Facilities

Duration: xx minutes (x Videos at x minutes each) This video was part of the LSUG: Cleanroom Environmental Monitoring Masterclass held on October 1, 2020, featuring John Wallingford of Pharmagraph.

October

Multi-Color Solution for Flow Cytometry

Duration: 56 minutes 49 seconds Webinar. Empower your multicolor panel design with tools and techniques from Beckman Coulter.

May

Multi-Sizing your Multi-Color for Panel Design

Duration: 55 minutes 9 seconds

Multi-parametric flow analysis provides tool for dissecting complex cell populations, identifying underlying mechanisms of disease and increasing test efficiencies. Optimal design critical for valid results.

May

Measuring Molecular Interactions by Multi-Wavelength AUC

Duration: 1 Hour 4 minutes 21 Seconds In this webinar, Dr. Demeler will provide an introduction into this new methodology, its computational challenges, and explain its benefits for the investigation of biopolymer interactions in the solution phase.

June

Combined Use of Multiple Particle Characterization Technologies to Evaluate Targeted Liposomal Formulations

Duration: 1 hour 6 minutes 46 seconds Multiple particle characterization technologies for evaluating targeted liposomal formulations webinar by Melvin E Klegerman.

May

English

On the Importance of Monitoring Both Transfection and Transduction Efficiencies in Cell Therapy Development

Duration: xx minutes (x Videos at x minutes each)

April

Optimizing Quality Control Electronic Records for 21 CFR Part 11 Compliance

Duration: 45 minutes 58 seconds

In this video, Beckman Coulter Product Manager Tony Harrison covers quality control records and 21 CFR Part 11, manual and electronic SOPs, final product QC, cleanroom environmental monitoring records and QC instrumentation electronic records.

February

English

Next Generation Polymer Dyes: Enhance your multicolor flow cytometry panels

Duration: 57 minutes Polymer dyes are now common tools used to design multicolor flow cytometry panels, however, many existing technologies do have drawbacks. In this session, Lucille Lassalle and Brice Ezzouaouy will introduce SuperNova Dyes, a new generation of polymer dyes designed to deliver ideal brightness, minimal non-specific staining and an optimal staining index. Learn about the unique properties of SuperNova Dyes and how they might help improve your flow cytometry panels, and review staining data, comparing SuperNova Dyes to other polymer dyes.

November

English

Particle Size Characterization by Laser Diffraction Analysis in Geoscience and Soil Science

Duration: 56 minutes 39 seconds Application of particle size characterization in the field of geoscience and soil science. Includes several case studies, discussion of preparation and treatment of materials prior to measurement and importance of subpopulations in wide particle size distributions. Dr. Björn Machalett gives this webinar.

May

English

Particle Size Distribution for Cement using Laser Diffraction

Duration: 48 minutes 2 seconds Importance of particle sizing in cement production. Using laser diffraction. Not all laser diffraction instruments are equal. Webinar presented by Edward Hoff.

May

English

Q&A Panel discussion, LSUG Lab and Pharma Water speakers

Duration: xx minutes (x Videos at x minutes each)

July

Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge

Duration: 55 minutes 52 seconds Webinar covers physical and chemical characterization of nanoparticle constructs using analytical ultracentrifugation. Webinar is presented by Osman M Bakr from King Abdullah University of Science and Technology.

May

English

Total Organic Carbon Analysis in the new ASTM E3106 Cleaning Standard

Duration: xx minutes (x Videos at x minutes each)

July

Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression

Duration: 50 minutes 14 seconds

Proteomics analysis of tumor microenvironment focused on primary fibroblast-derived exosomes in oral cancer progression presented by Simone Principe from Princess Margaret Cancer Center University Health Network.

May

English

Real-Time Detection of Bioburden & Biofilm in Water Systems

Duration: xx minutes (x Videos at x minutes each)

July

Quantifying Protein Aggregates by Sedimentation Velocity

Duration: 51 minutes 28 seconds Webinar covering protein aggregate quantification by sedimentation velocity by Michael Stoner PhD of Amgen - PART I. AUC instrumentation & protein aggregate quantification; PART II. Size exclusion chromatography vs sedimentation velocity; PART III. Simulation as a tool for understanding results.

May

English

ICH Q2 Validation of On-line TOC Analyzers

Duration: 23 minutes 59 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses the validation of on-line TOC analyzers for product release testing using ICH Q2.

January

English

Duration: xx minutes (x Videos at x minutes each)

February

Russian

Identifying and Isolating Stem Cells Through High-Speed Cell Sorting

Duration: 54 minutes 48 seconds Webinar. A discussion of stem cells covering range of topics and cell types from E. Michael Meyer.

May

English

New Strategies to Improve Your CE-SDS Results: A Data-driven Perspective

Duration: 56 minutes 3 seconds This webinar presents new strategies for improving your CD-SDS results including bioproduct analytical testing and a Biomek dilution program. This webinar is presented by Kevin Overstreet at Eli Lilly.

May

English

New Automation Strategies For Improving Sample Prep - The Analytical Laboratory

Duration: 9 minutes 46 seconds This presentation by Michael Kowalski at Beckman Coulter Life Sciences covers automation of capillary electrophoresis and mass spectrometry workflows for the analytical laboratory. Learn how the Biomek 4000 Workstation enables accurate sample prep, essential for downstream applications.

May

English

Leveraging acoustic and tip-based liquid handling to increase SARS-CoV-2 sequencing throughput

42 minutes 48 seconds

In this webinar recording, Dr. Eric Chow from UCSF explains how the ideal protocol requires a low-cost, high-throughput and simple workflow that is compatible with a wide variety of sequencing instruments.

February

Isolation and Characterization of Exosomes and Ectosomes

Duration: 1 hour 12 minutes 46 seconds Presentation from Suresh Mathivanan at La Trobe University covers practical insights and experience relating to exosome and ectosome isolation & characterization.

May

English

Isolation of Extracellular Vesicles: Latest Advances and Challenges

Duration: 58 minutes 30 seconds A webinar from Winston Patrick Kuo on advances and challenges in isolating extracellular (EV) vesicles. He highlights the need for streamlined, reliable and reproducible EV isolation for downstream studies.

May

English

Advanced Process Quality Control and Outlier Detection with Discrete Particle Analysis

Duration: 47 minutes 29 seconds Avanced process quality control and outlier detection with discrete particle analysis.Covers basic principles, the Coulter Principle and chemical/material applications.

May

English

Particle Counters Must Now be Calibrated With ISO 21501-4

Duration: 1 hour 2 minutes 56 seconds Overview on calibrating particle counters to 21501-4.

May

English

Nano-Emulsion Formulation and Characterization Life Science and Industrial Markets

Duration: xx minutes (x Videos at x minutes each)

This video was a webinar titled "Nano-Emulsion Formulation and Characterization Life Science and Industrial Markets" that was presented on May 27, 2020 featuring featuring

John Costello, Ph.D.
Edgard Martinez
Derek C. Lenz, Ph.D.

July

Particle Size and Associated Sedimentary Processes on Wetland Gain and Loss in the Mississippi River Delta

Duration: 1 hour 3 minutes 38 seconds Influence of particle size and associated sedimentary processes on wetland gain and loss in the Mississippi River Delta. This webinar is presented by Alexander S Kolker at Louisiana Unviersities Marine Consortium.

May

English

Cross-talk and Developmental Programs - A Key to Translational Stem Cell Biology

Duration: 1 hour 31 minutes 13 seconds Cellular signaling mediated by extracellular membrane vesicles in the application of stem cells as therapeutics.

May

Advances in Sedimentation Analysis by Dr. Borries Demeler

Duration: 1 hour 8 minutes 46 seconds This presentation covers advances in sedimentation velocity (SV) analysis including methods for accurately characterizing heterogeneous systems at high resolution; approaches to extract rich information from SV experiments and techniques to measure the strength of macromolecular interactions with discrete binding models to whole boundary SV experiments in analytical ultracentrifugation.

April

English

Automated Alternative to the Hanging Drop Method of Stem Cell Differentiation

Duration: 55 minutes 53 seconds

May

21 CFR Part 11 Data Integrity for Online TOC Instruments

Duration: 34 minutes 39 seconds Beckman Coulter Life Sciences sponsors a video on 21 CFR Part 11 data integrity for online TOC instrumentation, presented by Tony Harrison

September

English

Large Scale Purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation

Duration: 1 hour 1 minutes 45 seconds Webinar from Daniel Jasinski covers RNA nanotechnology in cancer therapy. RNA/RNA-based nanoparticle purification by ultracentrifugation including current technologies, different methods of ultracentrifugation, why large quantities of RNA are needed, methods for large-scale RNA purification.

May

English

ICH Q2 Validation of Analytical Procedures for Pharmaceutical TOC Analyzers

Duration: 31 minutes The tripartite International Conference on Harmonization (ICH) Q2 guide on validation of analytical procedures is not new, but it can give very good advice when validating laboratory Total Organic Carbon (TOC) analyzers for pharmaceutical use, especially when a user is considering changing analyzer brands or TOC analysis technologies. This webinar discusses how ICH Q2 can be applied to TOC analyzers to ensure they are suitable for pharmaceutical applications.

March

Is Immunotherapy Living up to its Promise?

Duration: 1 hour 24 minutes 9 seconds Watch this webinar on the advancements and performance of immunotherapy, presented by Jill O'Donnell-Tormey and Alex Y. Huang

May

English

Initial Evaluation of the ClearLLab 10C System in the Immunophenotyping of Leukemia and Non Hodgkin Lymphoma

Duration: 42 minutes 59 seconds In this webinar understand the process for routine cocktail selection and preparation, describe the key concepts in the ClearLLab 10 color system design, demonstrate using case studies the applicability of ClearLLab reagents and evaluate the results of the clinical accuracy study.

April

Hematopoietic Bone Marrow Cell Sorting without Compromise

Duration: 52 minutes 25 seconds Flow cytometry analysis and sorting are valuable techniques for studying distinct hematopoietic bone marrow populations. Webinar covers identification, isolation and purification of hematopoietic stem cells.

May

Kaluza Batch Analysis Tutorial with Dr. David Onion

Duration: 7 minutes 42 seconds In this Kaluza data analysis video the batch analysis gets explored. In a nutshell batch analysis allows you to use any, protocol file, composite, or Kaluza analysis file as a template to perform analysis on as many files as you like. This would become really useful if you were compiling reports, perhaps you’re writing a paper and you wanted to get all your data together and make sure it is analyzed in exactly the same way.

November

How Stem Cells Speak with Immune Cells

Duration: 1 hour 8 minutes 33 seconds Watch this webinar from Stefan Pluchino on how stem cells signal to the host immune system

May

English

Recent Advances in Immunotherapy: Directing Cells to Address Disease

Duration: 1 hour 10 minutes 2 seconds Watch this webinar on the recent advances in immunotherapy with a focus on directing cells to address disease, presented by Leena Gandhi MD PhD

May

English

Diamond-Based Nanomedicine for Enhanced Cancer Treatment and Imaging

Duration: 58 minutes 12 seconds This webinar covers the unique attributes of diamond-based nanoparticles and why they are effective when imaging for cancer and drug delivery as well as their in-vitro and in-vivo applications.

May

Duration: xx minutes (x Videos at x minutes each)

April

Russian

Diversity of Cancer-Derived Extracellular Vesicles

Duration: 59 minutes 59 seconds This webinar from Dr. Dolores Di Vizio covers extracellular vesicle heterogeneity, large oncosomes and potentials for biomarker development.

May

English

Diversity of Extracellular Vesicles and Their Cargo in Cell-To-Cell Communication

Duration: 1 hour 2 minutes 56 seconds Dr. Jan Lötvall discusses the study of extracellular vesicles and their relevance for cell-to-cell communication and how they have been implicated in several ways in disease progression. Understand the wide diversity of extracellular vesicles, with diverse morphology according to electron microscopy studies and difference in RNA and protein cargo according to bioinformatics analyses.

May

English

Emitting Dye for Violet Laser Excitation with Krome Orange

Duration: 29 minutes 50 seconds Krome Orange dye conjugates can be used on any flow cytometer equipped with violet excitation and appropriate emission filters. Data presented using Krome Orange conjugates of anti-human CD4, CD19 and CD45 in multicolor applications, including side scatter/CD45 gating and a 6-plus color stain. Krome Orange dye provides optimized second organic fluorochrome for violet excitation, enabling 10-color applications on the Gallios / Navios flow cytometer systems.

May

European Pharmacopoeia EP2.2.44 Total Organic Carbon

Duration: 28 minutes 41 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses European Pharmacopoeia and complete TOC oxidation for PW and WFI.

January

English

Evolution in the Manufacturing of Cellular Therapies

Duration: xx minutes (x Videos at x minutes each) Lessons learned and current solutions Immunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy, the result is an expanded population of T cells primed to recognize and eradicate malignant tumor cells that would otherwise escape immune detection. The webinar will discuss how cellular therapies have evolved, lessons learned through the evolution and current solutions available today. Learning Objectives: Commercialization of manufacturing- preparing a CAR Garage, lessons learned and how does it impact the patient. Automated functional testing- fully integrated unit operations taking the art out of science!

January

Cytobank Bootcamp Session #3 viSNE

Duration: 60 minutes This webinar demonstrates how to set up viSNE, optimize it and interpret the results within the Cytobank platform.

April

Cytobank Bootcamp Session #2 Data Management

Duration: 60 minutes This session provides specifics on data security, data pre-processing, exporting statistics, and figure generation within the Cytobank platform

April

Duration: xx minutes (x Videos at x minutes each)

February

Russian

Cytobank Bootcamp Session #5 Biomarker discovery with CITRUS

Duration: 59 minutes 29 seconds

Join us in learning how to utilize CITRUS algorithm for identification of differences between experimental groups

April

Duration: xx minutes (x Videos at x minutes each)

June

Russian

Duration: xx minutes (x Videos at x minutes each)

June

Russian

Pharmaceutical Water Production, Richard Jarrett, Evoqua Water Technologies

Duration: xx minutes (x Videos at x minutes each)

July

Meeting Global TOC and Conductivity Pharmacopeia Compliance while using ALCOA Requirements to Protect Data Integrity

Duration: xx minutes (x Videos at x minutes each)

This video was part of the annual LSUG Laboratory and Pharma Water Production event on June 23, 2020.

Featuring Paul Farrell of Beckman Coulter Life Sciences

July

Validation of Growth Direct to Perform Pharmaceutical Water Bioburden Analysis

Duration: xx minutes (x Videos at x minutes each)

This video was part of the annual LSUG Laboratory and Pharma Water Production event on June 23, 2020.

Featuring Susan Schilling of Rapid Micro Biosystems

July

Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses Using Analytical Ultracentrifugation

Duration: 1 hour 2 minutes 35 seconds Live broadcast covering applications of analytical ultracentrifugation (AUC).

May

English

Rethinking Data Analysis for Flow Cytometry with Kaluza 1.1 Software

Duration: 55 minutes 56 seconds Quickly and efficiently analyze multi-color, multi-parametric high content data generated by today's flow cytometers with revolutionary Kaluza analysis software.

May

Predictive power of CITRUS

Duration: xx minutes (x Videos at x minutes each) Learn how the power of CITRUS can identify and assign statistical significance to biological signatures that differentiate samples across multiple groups

21.03.1120.FLOW

March

Duration: xx minutes (x Videos at x minutes each)

April

Russian

Sample Prep for MS

Duration: 45 minutes 39 seconds This webinar covers automated Biomek solutions for mass spec sample prep.

April

English

Contemporary Cell Staining and Imaging Tools for Screening Stem Cell-Derived Cardiomyocytes

Duration: 59 minutes Webinar presented by Beckman Coulter, Molecular Devices and Cellular Dynamics covers image-based cardiomyocyte assays including a comprehensive toolbox and complete image solution for your image analysis needs.

May

Reducing Human Errors in Pharmaceutical Manufacturing Quality Control

Duration: 25 minutes 50 seconds Beckman Coulter Life Sciences sponsors a video on reducing human error in pharmaceutical quality control.

September

The Art of Sorting for Advancing Cytometry

Duration: 55 minutes 27 seconds Learn the basic elements for successful sorting: droplet breakoff, particle detection, sort decisions/delay, droplet charging and deflection.

May

Scaling-Up Exosomes and Other Extracellular Vesicles

Duration: 59 minutes

In this webinar, Derek C. Lenz, Ph.D. covers ways to take your EV production to the next level.

August

Take the Risk out of Rotations Understanding and Implementing BioSafety Solutions in Centrifugation

Duration: 57 minutes 20 seconds Watch Dr. Derek C. Lenz's webinar on Take the Risk out of Rotations Understanding and Implementing BioSafety Solutions in Centrifugation

April

Testing Vaccines Final Form Dose to USP<787> Subvisible Particulate Matter

Duration: 23 minutes A presentation on the challenges that fully implementing USP<787> presents to liquid particle counters with inherently large tare volumes, poor sample-to-sample repeatability with such low sample volumes and inability to precisely deliver small volumes.

December

The Future of Liquid Handling Automation has Arrived

Duration: 59 minutes 2 seconds First webinar in a three-part series introducing the new Biomek i-Series Automated Workstations. Two new liquid handlers designed to enable continuous innovation for tackling the ever-changing demands of life science research in mid- to high-throughput labs. Meet the product development team and learn more about new solutions. Q&A included. Additional webinars cover how i-Series solutions can accelerate a range of applications.

May

The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems

Duration: 1 hour and 10 minutes

September

The Power of Automated Assay Optimization

Duration: 39 minutes 11 seconds This webinar addresses the topic of automated assay optimization - what it is, why do it and benefits realized.

May

Transferring Cell Counting Methods: Best Practices

Duration: xx minutes (x Videos at x minutes each)

April

The Role of Exosomes in Inflammatory Disease - Pathogenesis and Treatment

Duration: 1 hour 19 minutes 41 seconds This webinar covers the biology of exosomes and how they are involved in inflammatory diseases. Exosomes as biomarkers and therapeutic agents.

May

English

Understanding the How and the Why: Biosafety in Centrifugation

Duration: 59 minutes This webinar will address potential gaps, review proper use and maintenance of centrifuges, rotors, and labware with a focus on BioSafety (42 CFR part 73). The intent is to provide information to assist with utilizing centrifugation in a more productive and safe manner.

October

The Science of Flow Cytometry Part 1

Duration: 53 minutes 44 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 1.

May

qPCR Webinar: Scalable Workflows for Viral RNA Extraction and Reaction Setup

Duration: 40 minutes 18 seconds Watch the collaboration between Beckman Coulter Life Sciences and IDT for the solutions to qPCR sample prep, featuring viral RNA extraction reagent kits.

August

The Science of Flow Cytometry Part 2

Duration: 55 minutes 53 seconds

Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 2.

May

Seminar: Advanced Sensitivity and Resolution in Flow Cytometry through Innovation

Duration: 1 hour 21 minutes 46 seconds J. Paul Robinson from Purdue University describes the innovations borrowed from the telecommunications industry that are being applied to flow cytometry. The unique collection of technologies are fueling the miniaturization of flow cytometry instruments while increasing the sensitivity and resolution of detected particles.

April

Environmental Cleanroom Monitoring & 21 CFR Part 11 Data Integrity

Duration: 33 minutes 20 seconds This webinar was presented by Beckman Coulter Life Science' Tony Harrison on July 27 2020.

May

English

Three Distinct Analytical Ultracentrifugation Methods for Virus and Viral Vector Characterizations

Duration: 33 minutes 5 seconds Sedimentation velocity analytical ultracentrifugation (SV-AUC) is considered the gold standard method for the size distribution analysis of viral vectors for gene therapy, but you have other orthogonal AUC methods to choose from too, including band sedimentation AUC (BS-AUC) and density gradient equilibrium AUC (DGE-AUC).

September

Webinar: NanoGBS—A Miniaturized Procedure for Genotyping by Sequencing Library Preparation

Duration: 44 minutes and 20 seconds

High-throughput reduced-representation sequencing (RRS)-based genotyping methods, such as genotyping-by-sequencing (GBS), have provided attractive genotyping solutions in numerous species. In this webinar, Davoud Torkamaneh, PhD, assistant professor at Université Laval, will discuss NanoGBS, a miniaturized, eco-friendly method for GBS library construction.

March

Changes to USP <643> Total Organic Carbon for Pharmaceutical Grade Waters

Duration: xx minutes (x Videos at x minutes each)

A revised version of the USP chapter on Total Organic Carbon (TOC) USP<643> was published recently and will become official on 1st May 2021. This paper gives an overview of this new USP chapter and discusses the reasoning behind the difference in the System Suitability Test materials called for in USP<643> and those in the Japanese JP16.

Learning Objectives:

Learn about the revised USP chapter on Total Organic Carbon (TOC) USP<643> which will become official on 1st May 2021
Learn about the System Suitability Test in USP<643>
Learn the reason why Japanese Pharmacopoeia calls for different System Suitability Testing materials to USP

May

English

Understanding the Role and Benefits of Centrifugation in Cell Harvest and Separation

Duration: 36 minutes In this webinar we will provide an overview of technology for primary recovery, considerations for choosing equipment, and tips and tricks to improve your process.

March

Clinical Flow Cytometry User Group Meeting

Duration: 2 hours 00 minutes

Learning Lesson 1 – The Healthy Immune System (Dr. Lisa Holey, Clinical Solutions Manager, Beckman Coulter Life Sciences)

Learning Lesson 2 – How to Identify Aberrant Cells (Sandra Hernandez, Product Manager, Beckman Coulter Life Sciences)

Technical Session – Plasma Cell Testing for Myeloma MRD Analysis (Mike Sutter, Technical Specialist, Pathology Consultants)

December

English

Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy

Duration: 46 minutes 34 seconds Understand the role viral vectors play in modern gene research and how ultracentrifugation is used to produce these key delivery systems

May

English

Cytobank Webinar - CITRUS in Practice with Dr. Anna Belkina

Duration: 57 minutes 29 seconds Special guest Dr. Anna Belkina, Associate Director of the Flow Cytometry Core at Boston University, outlines her approach and results, as published in Frontiers in Immunology: “Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging”.
See how the CITRUS algorithm can perform robust statistical analysis without requiring code, and understand how CITRUS can be applied to reveal unexpected findings from your dataset with the Cytobank platform.

November

GMP Cleanroom Routine Environmental Monitoring & 21 CFR Part 11 Data Integrity

Duration: xx minutes (x Videos at x minutes each)

August

Introduction to the New USP <787>: Subvisible Particulate Matter in Therapeutic Protein Injections

Duration: 1 hour 6 minutes 30 seconds An introduction to USP <787>: Purpose and differences between <787> and <788>, visible vs subvisible particles, methods and technology.

May

Duration: xx minutes (x Videos at x minutes each)

April

Russian

Cytometry data sharing platform for collaborative multi-centric data analysis

Duration: xx minutes (x Videos at x minutes each) In this webinar, Dr. LUCHE showcases the ease of data management and illustration design in the Cytobank platform, allowing fast interrogation of multi-group multi-sample datasets.

April

Overcoming the Hurdles of Density Gradient Ultracentrifugation for Optimized Gene Therapy Purification Workflows

Duration: 51 minutes 6 seconds Learn about the various types of density gradients techniques, how they are used, and how to get started as well as how to design and optimize a density gradient ultracentrifugation workflow, with AAV and plasmid DNA purification as examples.

March

English

Looking Under the Hood: Getting Started with the Optima AUC

Duration: 56 minutes 5 seconds In the webinar we discuss the fundamentals of analytical ultracentrifugation and look at a few sample applications.

October

Webinar: An Intro to Characterization of Biomolecules Using AUC

Duration: 60 minutes 13 seconds Analytical Ultracentrifugation (AUC) is one of the most powerful biophysical tools used today for the characterization of biological samples ranging from small drug molecules to intact viruses, vesicles and microparticles

October

Characterizing Viral Vector Fullness in Density Gradient Separations

Duration: 30 minutes Known as density gradient equilibrium analytical ultracentrifugation (DGE-AUC), it’s a simplified method that provides high-resolution benefits along with numerous advantages over the current gold standard sedimentation velocity AUC. Watch webinar to learn more.

July

Machine Learning Assisted Population Identification

Duration: xx minutes (x Videos at x minutes each) Leverage machine learning to identify novel cell populations and integrate single-cell technologies. Describes the application of a pipeline data analysis to increase consistency for multisite studies applied to overcome challenges due to CD4+ T cell plasticity.

May

The Revised ISO 14644-1 Changes Classification and Monitoring Methods

Duration: 1 hour 16 minutes 55 seconds ISO 14644-1: Impacts on classification methods and monitoring strategies presented by Joe Gecsey.

February

Webinars

Cell-Free Technology and Acoustic Liquid Handling Are Helping Tierra Disrupt Natural Product Discovery

An End-to-End Automated Workflow for High-Throughput SARS-Cov-2 Sequencing and Surveillance

Cell Counting & Viability: Faster Results Through Automation

Avoid Pitfalls When Automating Cell Viability Counting for Biopharmaceutical Quality Control

Changes to USP <1788>: Determination of Subvisible Particle Matter from the HIAC and Coulter Counters

Taking the Tricky Out of Automating NGS Sample Prep

Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler

Automation-Enabled LC-MS Analysis of Biologics

Characterization of CRISPR Technologies Using Cell-Free Transcription and Translation and an Acoustic Liquid Handler

Characterization of Extracellular Vesicles with Nanoscale Flow Cytometry

Automation of PCR Setup and AMPure XP Purification using the Biomek 4000 Workstation

Characterizing Viruses: From Deadly Pathogens to the Workhorses of Gene Therapy

Avoiding the Perils of Hidden Requirements

Choosing the Right TOC Analyzer for a Pharmaceutical QC Laboratory

Basic Research Signaling Applications

The Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals

Analytical Ultracentrifugation in the Biopharmaceutical Industry

Analytical Ultracentrifugation in Nanoparticle Analysis

Addressing the Challenges of Purification & Quality Control in Gene Therapy

Analytical Ultracentrifugation of Carbon Nanotubes

Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry

Analytical Methods to Measure Empty and Full AAV Particles

Automated Assays For Protein Engineering, In Vitro And In Vivo, By Dr. Daniela Quaglia

Applications of Counterflow Centrifugal Elutriation CCE

Automated High-Throughput and High-Content Analysis by Flow Cytometry

Using Data to Drive Automated Screening and Effective Reporting

Automating Continuous Cell Culture by Dr. Oliver Gassmann

Exosome Biogenesis and the Budding of Proteins and Viruses

High-Performance Exosome Purification and Characterization via automated Density Gradient

Exploring Exosomes and the Tumor Microenvironment

Fast Cost-Effective High Throughput Solutions for DNA Assembly

Exploring the Stoichiometry of Macromolecular Complexes Using Multi-Signal Sedimentation Velocity Analytical Ultracentrifugation

Extracellular Vesicle Isolation by Flow Cytometric Sorting and Characterization by Analytical Ultra-Centrifugation and Dynamic Light Scatter

Fluorescent amplification for next generation sequencing (FA-NGS) library preparation: A Streamlined Workflow to Improve NGS Quality Control Testing

Extracellular Vesicles Delivery and RNA Translation

Fully Automated RNA Library Preparation for Sequencing Respiratory Viruses

Advanced Flow Cytometric Analysis of Human T-Cell Memory Subsets

Goldilocks & the Three Cells: The Art of Monitoring & Managing Cell Cultures

Flow Cytometry Data Analysis in a Flash

ICH Q2 Validating a TOC Analyser with the QbD1200

Gallios Flow Cytometer Forward Angle Light Scatter Innovation

Cleanroom Routine Environmental Monitoring & Classification

Cytobank Bootcamp Session #6 Single Cell Data

Cytobank Bootcamp Session #4 FlowSOM

Cytobank Bootcamp Session #1 Introduction to Cytobank

Cellular Analysis Using the Coulter Principle

Cell Cycle Analysis by Quantitative Imaging Cytometry

Centrifugal Elutriation - Utility in the Flow Cytometry Laboratory

Contamination Control in the Hydraulic Industry

Data Insights for Automated Liquid Handling

Analysis of Cell Biochemical Processes from First Principles to Cytometry

ACFTD Discontinuance and the HIAC 8011+ and HIAC PODS+

Analysis of Particle Size Distributions by Analytical Ultracentrifugation

Achieving Cell-Free Gene Expression with An Acoustic Liquid Handler

Analytical Ultracentrifugation For Structural Analysis - Proteins and Macromolecular Complexes

Laser Cytometry in Biomedical Analysis

Cleanrooms: Controlling Contamination, Setting Alerts & Actions, Considerations of Removal Efficiency

Leveraging the Value of Automated High-Content Screening

Microvesicle Detection and Cell Sorting

GMP Cleanroom Routine Environmental Monitoring & 21 CFR Part 11 Data Integrity

Monitoring Signal Transduction Pathways in Human Disease

Particle Monitoring Systems for Isolator / RABS Filling Lines and 503B Compounding Facilities

Multi-Color Solution for Flow Cytometry

Multi-Sizing your Multi-Color for Panel Design

Measuring Molecular Interactions by Multi-Wavelength AUC

Combined Use of Multiple Particle Characterization Technologies to Evaluate Targeted Liposomal Formulations

On the Importance of Monitoring Both Transfection and Transduction Efficiencies in Cell Therapy Development

Optimizing Quality Control Electronic Records for 21 CFR Part 11 Compliance

Next Generation Polymer Dyes: Enhance your multicolor flow cytometry panels

Particle Size Characterization by Laser Diffraction Analysis in Geoscience and Soil Science

Particle Size Distribution for Cement using Laser Diffraction

Q&A Panel discussion, LSUG Lab and Pharma Water speakers

Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge

Total Organic Carbon Analysis in the new ASTM E3106 Cleaning Standard

Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression

Real-Time Detection of Bioburden & Biofilm in Water Systems

Quantifying Protein Aggregates by Sedimentation Velocity

ICH Q2 Validation of On-line TOC Analyzers

Identifying and Isolating Stem Cells Through High-Speed Cell Sorting