Mass Spectrometry

Innovating mass spectrometry sample prep through automation

Proteomics research presents issues of limited and variable sample material and degradation, vast dynamic range and a plethora of post-translational modifications. Whether analyzing a single protein or an entire proteome, automating the sample prep for mass spectrometry analysis can help achieve enhanced reproducibility while also delivering cost- and time-saving benefits.

The Biomek liquid handling systems present a dynamic range of pipetting capabilities that can be configured for semi- or complete automation for your sample prep for mass spectrometry analysis.

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Automated salt-assisted liquid-liquid extraction In this work, we have utilized a Biomek NXP Workstation to automate the liquid handling steps of salt-assisted liquid-liquid extraction of 25-OH-Vitamin D from serum
Automated Sample Preparation for the Monitoring of Pharmaceutical and Illicit Drugs by LC-MS/MS This application note describes results obtained using a liquid handling-based automation system for the sample preparation of compounds to be analyzed by LC-MS/ MS and applied to the monitoring of multiple classes of pharmaceutical and illicit drugs.
Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS In this application note, we describe an LC-MS/MS method for the analysis of EtG and EtS in urine employing a simple, automated sample preparation methodology using a liquid handling-based automation system.

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